Ejvind Mortz, PhD

COO and Co-founder of Alphalyse

Ejvind Mørtz is a leading figure in proteomics and mass spectrometry analysis with more than 30 years of experience in biotechnology and protein biologics development. He holds a PhD in Protein Chemistry and Molecular Biology from the University of Southern Denmark. He has specialized in developing innovative protein analysis methods for chemistry, manufacturing, and control (CMC) development of protein biologics and complex products like gene therapies.

Ejvind published his first article on protein identification using mass spectrometry in 1994 and has since co-authored close to 50 scientific articles on host cell proteins and mass spectrometry (LC-MS) analysis. His research has earned more than 3,200 citations in academic literature and has been instrumental in shaping best practices for protein analysis by LC-MS, now recommended in the US Pharmacopeia General Chapter <1132.1> for improving the quality and safety of biologics manufacturing.

As an expert in the field, Ejvind has been invited to speak at numerous industry conferences. His contributions include talks at the BEBPA HCP Conference (2016, 2019, 2020, 2022, and 2023), the Bioprocessing Summit (2019), CASSS (2018), and many others.

Insights from the 2026 BEBPA Host Cell Protein Conference

BEBPA 2026 HCP Conference Highlights: Insights from Alphalyse

What's new? The latest on HCP analysis by MS from the 2026 BEBPA HCP Conference.
Accelerating early-stage process development:

Accelerating early-stage process development: eleva case study

Detecting and quantifying HCPs in a moss-based system
Victor et. al 2025

Open Access article: Comparison of USP 1132.1 quantitation methods

Experimental demonstration of LC-MS methods in USP 1132.1
Webinar USP 1132.1 with Victor Chrone Alphalyse

Webinar: Comparison of 3 USP 1132.1 MS quantitation methods

WEBINAR: Experimental demonstration of USP methods
Polysorbate-degrading host cell proteins

Webinar: Polysorbate-degrading HCPs

Latest research on PS-degrading HCPs and regulatory revisions impacting mAb products
Investigate polysorbate degrading HCPs

Poster: Sensitive MS-based lipase assay for mAb products

Sensitive MS-based MRM assay to detect polysorbate-degrading HCPs in mAb products
HCP-ELISA reagent characterization using LC-MS

Webinar: ELISA reagent characterization using LC-MS

Get a detailed understanding & documentation of the HCP-ELISA reagents' suitability to the specific manufacturing process
Ejvind Mortz presents at BEBPA 2023

Ejvind Mortz, COO, to present at BEBPA HCP conference 2023

How to characterize a ELISA antibody coverage and HCP standard
Vaccine HCP analysis

Webinar: Analyzing vaccine purity – without an HCP ELISA

Learn how to quickly measure & compare residual protein in any type of vaccine
2021 gtp webinar

Webinar: Monitoring impurities and ensure consistent therapies

Quickly identify and quantify all proteins in complex products using only one assay
process-related impurities

Article: Monitoring process-related impurities in biologics

HCP control strategies used in regulatory license applications presented by case studies
Principle of ELISA-MS

Blog post: How to select an HCP ELISA with sufficient coverage

Coverage analysis with only 0.5 mg antibody and without a mock cell line
Antibodies

Blog post: Investigation of ubiquitin in purified antibody products

Characteristics and implications of ubiquitin - and how to detect it
gtp webinars

Webinar: Are you ready for FDA questions about impurities?

FDA guidelines for process-related impurities in cell & gene therapies.
Analysis of HCPs in process samples by mass spectrometry

White paper: HCP analysis of downstream process samples by LC-MS

written by Rikke Lund, Ejvind Mortz, Thomas Kofoed et. al
common protein residues

Blog post: How to document removal of a process related impurity

Terrific method with detection limits down to low ppm levels
3 reasons to check the coverage of your HCP-ELISA

Webinar: 3 reasons to check the coverage of your HCP-ELISA

Using ELISA-MS™ for detecting which individual impurities are measured

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