Ejvind Mortz, PhD
COO and Co-founder of Alphalyse
Ejvind Mørtz is a leading figure in proteomics and mass spectrometry analysis with more than 30 years of experience in biotechnology and protein biologics development. He holds a PhD in Protein Chemistry and Molecular Biology from the University of Southern Denmark. He has specialized in developing innovative protein analysis methods for chemistry, manufacturing, and control (CMC) development of protein biologics and complex products like gene therapies.
Ejvind published his first article on protein identification using mass spectrometry in 1994 and has since co-authored close to 50 scientific articles on host cell proteins and mass spectrometry (LC-MS) analysis. His research has earned more than 3,200 citations in academic literature and has been instrumental in shaping best practices for protein analysis by LC-MS, now recommended in the US Pharmacopeia General Chapter <1132.1> for improving the quality and safety of biologics manufacturing.
As an expert in the field, Ejvind has been invited to speak at numerous industry conferences. His contributions include talks at the BEBPA HCP Conference (2016, 2019, 2020, 2022, and 2023), the Bioprocessing Summit (2019), CASSS (2018), and many others.
Key publications:
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism. Nat Commun 5, 3369 (2014)
Proteomics Technology Applied to Upstream and Downstream Process Development of a Protein Vaccine, BioProcess International 2008
Improved silver staining protocols for high sensitivity protein identification using matrix-assisted laser desorption/ionization-time of flight analysis, 2001
Webinar: Polysorbate-degrading HCPs (on-demand)
Poster: Sensitive MS-based lipase assay for mAb products
Webinar: Problematic HCP impurities can stop your biologics project!
Webinar: ELISA reagent characterization using LC-MS
Ejvind Mortz, COO, to present at BEBPA HCP conference 2023
Webinar: Analyzing vaccine purity – without an HCP ELISA
Webinar: Monitoring impurities and ensure consistent therapies
Article: Monitoring process-related impurities in biologics
Blog post: How to select an HCP ELISA with sufficient coverage
Blog post: Investigation of ubiquitin in purified antibody products
Blog post: Why measure process-related impurities in gene therapies with LC-MS?
Webinar: Are you ready for FDA questions about impurities?
Article: Novel approach to evaluate ELISA antibody coverage of HCPs
White paper: HCP analysis of downstream process samples by LC-MS
Webinar: Design the optimal strategy for analyzing Host Cell Proteins
Blog post: How to document removal of a process related impurity
Webinar: 3 reasons to check the coverage of your HCP-ELISA
Blog post: Can I use commercial HCP ELISA kits in clinical trial documentation?
Blog post: What are Host Cell Proteins (HCPs)?
Blog post: Simple way to perform label-free quantification of Host Cell Proteins
Blog post: Identification of small host cell proteins (small Mw HCPs) – using mass spec
Blog post: 4 things to remember about Amino Acid Analysis
Alphalyse presents at BEBPA Conference in Lisbon
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