Our team of experts

We aim to provide our clients with the best protein analysis service by providing access to our service-minded team of highly experienced and skilled scientists, hand-picked from leading universities and companies, to cover protein chemistry, mass spectrometry, and bioinformatics. We apply top-of-the-line equipment and are experts in the interpretation of data for biopharmaceutical protein characterization.

team of experts

Management

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Thomas Kofoed

Co-founder and CEO

Thomas holds a PhD in Organic Chemistry and a BSc in Business Administration. He has 20+ years of management experience in the biotech industry and has set up business relationships with hundreds of biopharmaceutical companies. As CEO of Alphalyse, his main emphasis is putting together a diverse team of highly skilled employees creating an innovative environment focusing on quality and customer needs.

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Ejvind Mørtz

Co-founder and CEO

Ejvind holds a PhD in Protein Chemistry & Molecular Biology. He has more than 20 years of experience in several biotech companies. His background counts the development of protein analysis methods in research & CMC development of protein biologics and business collaboration with CMOs/CROs. He is driving the development and improvement of analysis services for our customers. Ejvind has a Business Executive education from Harvard Business School.

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Jette Friis Thirup

Head of Business Development

Jette holds a bachelor’s degree in International Business Administration. She has 20 years of experience in international marketing strategy & execution. She has substantial experience growing international medico and biotech businesses and building online channels in the USA and Europe and has planned multiple worldwide product launches. Jette has also managed several large-scale digitalization implementations.

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Rikke Raaen Lund

Head of Impurity Analysis Dpt

Rikke has a PhD in Biomedicine. She has broad experience in bioanalytical methods and clinical proteomics after more than ten years of work focusing on protein biomarker analysis, mass spectrometry, and handling large data sets. She is our expert in impurity analysis, i.e., host cell and residual protein analysis, of biopharmaceuticals and heads the development of improved impurity analyses using mass spectrometry, ELISA, and immuno-purification techniques.

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Anette Rasmussen

Head of Customer Service and Administration

Anette has a BSc in Biomedicine. She has extensive protein chemistry and mass spectrometry knowledge, with a particular flair for customer service and laboratory organization. Anette specializes in protein identification workflows, protein digestion, and laboratory robotics – gathered over more than ten years. She is your go-to person for customer support and questions related to sample submissions.

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Stine Thyssen

Head of Analytical Characterization Dpt

Stine has a PhD in Health Science. She has a background in biomedicine, redox biology, protein chemistry, and mass spectrometry. She is experienced in LC-MS/MS-based analysis of post-translation modifications, chemo-proteomics, protein, and peptide purification using various chromatographic methods, cell culturing, and extensive dataset analysis. Her primary focus is characterization projects and the development of novel mass spectrometry analyses.

Project leaders

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Dean Malte Pedersen

MSc in Biochemistry and Molecular Biology

Dean has an academic and industrial background in protein chemistry and mass spectrometry. He has experience analyzing nanoparticle-protein complexes and Host Cell Proteins in drug substances using mass spectrometric approaches and working with GMP and QC systems. At Alphalyse, Dean works as a principal investigator and assists in maintaining the mass spectrometers.

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Freja Andersen

MSc in Biomedicine

Freja’s specialties include immunological techniques, protein expression and purification, vaccine development, and protein analysis methods such as ELISA, SDS-page, and HPLC. She has industrial experience with research and production to GMP standards, Quality Control Systems, method validation, and preparation of GMP documentation. At Alphalyse, Freja works as a principal investigator and specializes in setting up GMP-related workflows.

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Janne Skaarup Crawford

BSc in Cell Biology and Biochemistry

Janne has comprehensive experience in proteomics, biotechnology, and protein analytics by LC-MS. The experience has been gathered during her 20 years in the biopharmaceutical industry, providing analytical services. She has significant expertise in quantitative LC-MS methods for MRM quantification of specific proteins in bioprocess samples. She is deeply involved in developing host cell and residual protein analyses by mass spectrometry.

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Anette Holck Draborg

PhD in Immunology

Anette is highly educated in immunology, virology, and autoimmunity. During her PhD, she focused on systemic autoimmune diseases and method development of immunochemical assays. Her methodological expertise includes ELISA, flow cytometry, cell culture, and various blotting techniques. At Alphalyse, Anette is an expert in immunopurification and ELISA coverage assay projects.

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Rie Bak Jäpelt

MSc Pharmacy, PhD Analytical Chemistry

Rie has worked with the development of quantitative mass spectrometry-based assays for more than ten years. Alphalyse also uses her immense experience with assay qualification and validation from implementing quality protocols and achieving accreditations. Rie has an interdisciplinary background in food science and genetics and expertise from academia, diagnostics, and the pharmaceutical industry.

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Solveig Beck Nielsen

PhD in Molecular Biology

At Alphalyse, Solveig drives new analysis services for host cell protein analysis using ELISA and mass spectrometry. Solveig obtained her PhD with a focus on biopharmaceutical science and molecular medicine. Her background is in the expression and purification of monoclonal antibodies and antibody characterization by immunochemistry methods.

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Sai Sindhu Thangaraj

PhD in Cardiovascular Inflammation

Sindhu has an industrial and academic background specializing in mAbs and recombinant proteins, immunology, and vaccinology. Her vast expertise includes protein expression & purification, antibody production & characterization, vaccine formulation & candidate screening, and handling of animal models. Sindhu also masters cell culturing, microsurgery, and the development of ELISAs and multiplex immunoassays.

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Line Koch

PhD in Health and Medical Sciences

Line holds a PhD in Health and Medical Sciences, focusing on molecular interactions concerning neurodegenerative diseases. Her protein characterization background encompasses biophysical and structural techniques, e.g., bioassays and liquid chromatography. At Alphalyse, Line uses her knowledge to develop and optimize protein and peptide characterization methods, focusing on HPLC optimization.

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Tine Nielsen

MSc in Biomedicine

Tine has experience in LC-MS/MS-based analysis of post-translational modifications, chemical modification (particularly cross-linking), structural characterization, and quality control position with GMP. At Alphalyse, Tine’s focus is MS, intact mass and amino acid analysis, maintenance of the instruments, and developing and optimizing protein and peptide characterization methods.

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Christina Erika Hagensen

PhD in Biochemistry and Molecular Biology

During her PhD, Christina explored cellular signaling networks for stem cell and skeletal muscle differentiation. She has extensive practical experience with cell culturing, LC-MS/MS, biological interpretation of large-scale proteomics, and GMP-required quality control. At Alphalyse, Christina works as a principal investigator and specializes in handling custom-designed HCP projects.

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Maša Babović

PhD in Biochemistry and Molecular Biology

For her PhD, Maša developed mass spectrometry methods for therapeutic protein characterization. She has extensive practical experience with process optimization, LC-MS method development, data analysis, intact mass and post-translational modification analysis, and stability and forced degradation studies. At Alphalyse, Maša is a principal investigator, focusing on process optimization and analytical method development.

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Melissa Fernard Pedersen

MSc in Medicine with Industrial Specialization

Melissa has extensive experience with ELISA, immunoprecipitation, and other immunological methods, as well as HPLC and protein characterization. Previously, she has researched biomarker assays for patient diagnostics and has worked with quality management systems for in vitro diagnostic assays as a QA specialist. At Alphalyse, Melissa is a principal investigator in our HCP-ELISA characterization team.

Client relations

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Martin Rask Johansen

Client Relations Manager - Protein Analysis

Martin has an MSc in Biochemistry and Molecular Biology specializing in mass spectrometry-based metabolomics and lipidomics . He also has practical experience with protein analysis, cell biology, immunology, and bioinformatics. At Alphalyse, he focuses on collaboration with new and existing biopharmaceutical clients, helping them settle on the proper analysis for their needs, and facilitating contact with our team of experts.

Specialists

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Flemming Holm Bergholdt

Biomedical Laboratory Scientist

Flemming has a broad technical background and 20 years of practical experience with clinical genetics and immunology, working with method development and research. He specializes in techniques such as HPLC, PCR, MLPA, Microarray, bacterial/cell-culturing, lentivirus production, cloning, and antibody sequencing. At Alphalyse, he mainly focuses on ELISA, Host Cell Protein, and HCP Coverage analysis projects.

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Sigurd Frederiksen

Biomedical Laboratory Scientist

Sigurd holds an MSc in Biochemistry and Molecular Biology and has a vast background in mass spectrometry and proteomics methods on advanced mass spectrometers. He has acquired extensive knowledge on characterizing single proteins, focusing on MS/MS fragmentation analysis of peptides and posttranslational modifications. At Alphalyse, Sigurd makes sure we utilize the full potential of our instruments and methods.

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Line Greve

Biochemical Laboratory Scientist

Line has 15+ years of practical experience in clinical immunology and molecular biology, with a particular focus on systemic autoimmune diseases and method development of immunochemical assays. At Alphalyse, Line specializes in working with laboratory optimization and validation, as well as immunoassays for protein analysis following GMP standards.

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Thanh Ha Nguyen

Biochemical Laboratory Scientist

Thanh has a university degree in biotechnology, protein chemistry, and mass spectrometry and fifteen years of experience in the analytical characterization of biopharmaceutical proteins and vaccines. Thanh’s primary expertise is detailed protein characterization for sequence verification using a combination of mass spectrometry, Edman sequencing, and amino acid analysis.

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Vicki Nautrup Nielsen

Biochemical Laboratory Scientist

Vicki has a broad technical background and more than 20 years of practical experience in clinical immunology and molecular medicine. She specializes in working with laboratory optimization and automation, immunoassays for protein analysis, expression and purification of recombinant proteins and antibodies. In addition, she is familiar with animal models, cell lines, and biopharmaceutical characterization using various chromatographic methods.

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Bente Marianne Jensen

QC Laboratory Manager

Bente has an MSc in Chemistry, Biochemistry and Molecular Biochemistry, and a PhD in Food Chemistry. She has extensive experience as a QC chemist, with a focus on analytical method development and implementation, instrumentation validation and qualification, and optimization of workflows. At Alphalyse, Bente works with MRM analyses under GMP conditions.

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Esben Fisker

QA Manager

Esben holds an MSc in Chemistry and is responsible for continuously developing the pharmaceutical quality system at Alphalyse. He has ten years of experience in the pharmaceutical industry and brings a diverse skill set in quality assurance, quality control, qualification, validation, and statistical process control. Esben drives the process of obtaining a GMP Authorization for Quality Control of pharmaceutical products at Alphalyse.

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Vasileios Tsiamis

Manager, Bioinformatics team

Vasileios has worked extensively with quantitative, statistical, and downstream analysis of MS-based proteomics data through his time in academia. He thrives with large and complex datasets, utilizing various programming languages to extract and evaluate data. He develops tools for us to quickly analyze datasets generated by mass spectrometry and combines data from our many HCP projects.

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Victor Chrone

Bioinformatics scientist

Victor has an MSc in Computational Biomedicine with experience in LC-MS/MS-based analysis of post-translational modifications and structural characterization. He has considerable experience with data mining, machine learning, data visualization, and protein chemistry. At Alphalyse, he will be working on developing bioinformatics tools to analyze mass spectrometric data.

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Cecilie Hovitz Lautrup-Larsen

Science Communication Specialist

Cecilie has a cross-disciplinary education combining BScs in Biomedical Laboratory Science and Medicine with an MA in International Science Communication. She has ten years of healthcare and medical research experience. As a communication specialist at Alphalyse, Cecilie specializes in information dissemination, digital marketing, and social media communication.

Talk to us

Whatever protein-related challenge or question you may have, we would love to help. Our experts can help you decide on the best analytical approach for your project by email or online meeting - providing advice without obligation.

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